Performance - Max Number of Assigned classes?

Hi All- 

Im curious if there is a known limitation/best practice for how many 300 classes can be assigned to a model?

In perusing the forums I have found limitations for other objects (>9999 objects assigned to classes, etc) and mentions of splitting large classes into smaller classes for better performance -- but is there a limit to this?

For example you can have a 1 (300) Class with 50 c'stics or 50 (300) Classes each with 1 c'stic assigned. Granted this is an over-simplified example to just serve my curiosity - has anyone modelled like this before? Any pitfalls/drawbacks/concerns? Benefits? 

Please add any thoughts or information around this - would love to hear anything offered !